Petrozza V, Passaro V, De Salazar C, Pulvirenti S, Riccardelli F, Magliocca F M
IV Cattedra di Anatomia ed Istologia Patologica, Università degli Studi di Roma La Sapienza.
Minerva Chir. 1994 Jan-Feb;49(1-2):89-94.
The authors describe a case of a submucosal lipoma of the large intestine. Family, physiological, and remote anamnesis of the patient was negative to inflammatory or neoplastic intestinal diseases. The symptomatology was not characteristic like the several cases reported in the literature, by abdominal cramps, subocclusion or total occlusion crisis and rectal bleeding. The patient presented with a symptomatology characterized by altered bowel habit, and evacuations of blood-stained feces. The clinical diagnosis was difficult for the aspecific symptoms referred. A barium enema and colonoscopy examination showed a suspected benign neoformation localized within the sigmoid colon. The patient underwent surgery and the following histologic exam exhibited a submucosal lipoma with an atrophied superficial epithelium replaced by necrotic and granular tissue, marked architectural disarray of glandular crypts and intensive inflammatory infiltrate of tunica mucosa.
作者描述了一例大肠黏膜下脂肪瘤病例。患者的家族史、生理史及既往史均未显示有肠道炎症性或肿瘤性疾病。其症状不像文献中报道的几例病例那样具有特征性，那些病例表现为腹部绞痛、不全梗阻或完全梗阻危象以及直肠出血。该患者的症状表现为排便习惯改变和排出血性粪便。由于所提及的症状不具特异性，临床诊断存在困难。钡剂灌肠和结肠镜检查显示在乙状结肠内有一个疑似良性新生物。患者接受了手术，随后的组织学检查显示为黏膜下脂肪瘤，其表面上皮萎缩，被坏死和颗粒状组织取代，腺隐窝结构明显紊乱，黏膜层有密集的炎症浸润。
