Chen E Y, Wilkins A J, McKenna P J
Fulbourn Hospital, Cambridge.
Psychol Med. 1994 Feb;24(1):193-202. doi: 10.1017/s0033291700026957.
The integrity of semantic memory in schizophrenia was examined in a reaction time task requiring subjects to verify words as members or non-members of a conceptual category, where the words differed in their degree of semantic relationship to the category. Compared to matched normal controls, 28 schizophrenic patients were impaired on the task, showing slower responses in all conditions. In addition, their performance was anomalous in that they took longest to respond to items that were outside the category but semantically related to it, in contrast to the controls who took the longest to respond to ambiguous words at the borderline of the category. The pattern of 'yes' and 'no' responses of the patients was anomalous in a similar way. In both speed and accuracy of responding, the findings indicate that there is an outward shift of semantic category boundaries in schizophrenia.
在一项反应时间任务中，研究了精神分裂症患者语义记忆的完整性。该任务要求受试者将单词验证为概念类别中的成员或非成员，其中单词与类别的语义关系程度不同。与匹配的正常对照组相比，28名精神分裂症患者在该任务中表现受损，在所有条件下反应都较慢。此外，他们的表现异常，即他们对类别之外但语义上与之相关的项目反应时间最长，而对照组对类别边界处的模糊单词反应时间最长。患者的“是”和“否”反应模式也以类似方式异常。在反应速度和准确性方面，研究结果表明精神分裂症患者的语义类别边界向外偏移。
