Mortensen P B, Eaton W W
Department of Psychiatric Demography, Psychiatric Hospital, Risskov, Denmark.
Psychol Med. 1994 Feb;24(1):223-32. doi: 10.1017/s0033291700026982.
Readmission risk was assessed at the first and subsequent discharges in a total Danish national sample consisting of 8705 first admitted patients who had been discharged alive at least once with a diagnosis of schizophrenia. Predictors for readmission risk were identified using the Cox proportional hazards model. Following the first discharge, 19% of the surviving patients had not been readmitted after 10 years of follow-up. Readmission risk increased with the number of previous admissions. At the first discharge readmission risk decreased with increasing age and was significantly predicted by clinical subtype and gender. At later discharges (5th, 10th, and 15th) the effect of these variables gradually disappeared. At the 15th discharge readmissions were mainly predicted by the duration of the latest admission and discharge periods. Both the increase in readmission risk with the number of previous admissions and the evolving pattern of predictors for readmission risk are interpreted as supporting the existence of a smaller subpopulation among schizophrenic patients with frequent relapses.
在丹麦全国范围内的一个总样本中，对8705例首次入院且至少有一次因精神分裂症诊断而存活出院的患者，在首次及随后出院时评估再入院风险。使用Cox比例风险模型确定再入院风险的预测因素。首次出院后，19%的存活患者在10年随访期内未再入院。再入院风险随既往入院次数增加而升高。首次出院时，再入院风险随年龄增长而降低，且受临床亚型和性别的显著预测。在随后的出院（第5次、第10次和第15次）时，这些变量的影响逐渐消失。在第15次出院时，再入院主要由最近一次入院和出院时长预测。再入院风险随既往入院次数增加以及再入院风险预测因素的演变模式，均被解释为支持在频繁复发的精神分裂症患者中存在一个较小的亚群体。
