Sohar E, Shoenfeld Y, Udassin R, Magazanik A, Revach M
Lancet. 1978 Nov 18;2(8099):1073-4. doi: 10.1016/s0140-6736(78)91805-6.
Two sisters whose parents shared a grandfather had cold-induced sweating. Since childhood they had sweated profusely from the back and chest when exposed to environmental temperatures of 18 degrees to 7 degrees C. They had additional abnormalities--e.g., high palate and inability fully to extend the elbows--which neither their parents nor their sibs shared. The cold-induced sweating, which could not be stopped by a beta-adrenergic blocking agent, was abolished by postganglionic blockade with atropine sulphate. This indicates the possibility of a peripheral mechanism.
父母是堂兄妹的两姐妹患有冷诱导出汗症。从童年起，当暴露于18摄氏度至7摄氏度的环境温度中时，她们的背部和胸部就会大量出汗。她们还有其他异常情况，比如高腭弓以及肘部无法完全伸直，而她们的父母和兄弟姐妹都没有这些情况。冷诱导出汗不能被β-肾上腺素能阻滞剂阻止，但用硫酸阿托品进行节后阻滞可消除这种出汗。这表明存在外周机制的可能性。
