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肾上腺素能刺激剂和阻滞剂对特应性皮炎和银屑病中汗腺分泌的影响。

Effects of adrenergic stimulating and blocking agents on the eccrine sweat secretion in atopic dermatitis and psoriasis.

作者信息

Thune P, Kocsis M

出版信息

Arch Dermatol Res (1975). 1975 Sep 12;253(2):97-103. doi: 10.1007/BF00582061.

DOI:10.1007/BF00582061
PMID:242278
Abstract

Quantitative measurements of eccrine sweat secretion following stimulation with adrenaline and terbutaline sulphate, a beta-stimulator, have been performed in patients with atopic dermatitis and psoriasis by means of the electrolytic water analyzer, "Meeco". Seasonal variations were demonstrated, the values being lower in the late autumn. The response to adrenaline could be blocked by phentolamine, an alpha-inhibitor, while propranolol, a beta inhibitor, had no effect.--The response to terbutaline was blocked by atropine and partly by practolol, a beta-inhibitor. Terbutaline induced a larger sweat response than isoprenaline, another beta-stimulator. A beta-receptor mechanism, in some way related to cholinergic receptors, is suggested.

摘要

通过“Meeco”电解水分析仪,对特应性皮炎和银屑病患者在肾上腺素和β-激动剂硫酸特布他林刺激后进行了外分泌汗腺分泌的定量测量。结果显示存在季节性变化,深秋时数值较低。肾上腺素的反应可被α-抑制剂酚妥拉明阻断,而β-抑制剂普萘洛尔则无作用。——特布他林的反应被阿托品阻断,部分被β-抑制剂普拉洛尔阻断。特布他林比另一种β-激动剂异丙肾上腺素诱导出更大的汗液反应。提示存在一种以某种方式与胆碱能受体相关的β-受体机制。

相似文献

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Effects of adrenergic stimulating and blocking agents on the eccrine sweat secretion in atopic dermatitis and psoriasis.肾上腺素能刺激剂和阻滞剂对特应性皮炎和银屑病中汗腺分泌的影响。
Arch Dermatol Res (1975). 1975 Sep 12;253(2):97-103. doi: 10.1007/BF00582061.
2
Effects of cholinergic and adrenergic blocking agents on the activity of the eccrine sweat glands.胆碱能和肾上腺素能阻断剂对小汗腺活动的影响。
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引用本文的文献

1
Thermal and sweating responses in normal and atopic subjects under internal and moderate external heat stress.正常人和特应性个体在内部和中度外部热应激下的体温及出汗反应。
Arch Dermatol Res. 1992;284(3):135-40. doi: 10.1007/BF00372705.

本文引用的文献

1
Physiological significance of the sweat response to adrenaline in man.人体对肾上腺素汗液反应的生理意义。
J Physiol. 1951 Aug;114(4):510-4. doi: 10.1113/jphysiol.1951.sp004640.
2
REGISTRATION OF THE INSENSIBLE PERSPIRATION OF SMALL QUANTITIES OF SWEAT.少量汗液不显性出汗的记录
Dermatologica. 1963;127:255-9. doi: 10.1159/000254866.
3
Eccrine sweating in psoriasis.银屑病中的小汗腺出汗
Br J Dermatol. 1969 Feb;81(2):119-24. doi: 10.1111/j.1365-2133.1969.tb15991.x.
4
A quantitative measurement of sweat production after local injection of adrenalin.局部注射肾上腺素后汗液分泌的定量测定。
J Invest Dermatol. 1971 May;56(5):384-6. doi: 10.1111/1523-1747.ep12261270.
5
Effects of cholinergic and adrenergic blocking agents on the activity of the eccrine sweat glands.胆碱能和肾上腺素能阻断剂对小汗腺活动的影响。
J Physiol. 1970 Nov;210(4):883-95. doi: 10.1113/jphysiol.1970.sp009247.
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Physiologic abnormalities in the atopic state: a review.特应性状态下的生理异常:综述
Ann Allergy. 1967 Apr;25(4):192-210.
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The effect of propranolol on the acetylcholine-induced sweat gland response in atopic and non-atopic subjects.普萘洛尔对特应性和非特应性受试者乙酰胆碱诱导的汗腺反应的影响。
Br J Dermatol. 1970 Aug;83(2):312-4. doi: 10.1111/j.1365-2133.1970.tb15706.x.
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The response of the sweat gland to acetylcholine in atopic subjects.
Br J Dermatol. 1970 Aug;83(2):306-11. doi: 10.1111/j.1365-2133.1970.tb15705.x.
9
The response of the sweat glands to beta-adrenergic stimulation with isoprenaline.汗腺对异丙肾上腺素β-肾上腺素能刺激的反应。
Br J Dermatol. 1974 Mar;90(3):263-8. doi: 10.1111/j.1365-2133.1974.tb06400.x.
10
Investigations of thurfyl nicotinate and methacholine reactions in atopic dermatitis by photoelectric reflectometry and plethysmography.
Arch Dermatol Forsch. 1974;250(4):285-94. doi: 10.1007/BF00558190.