经前综合征症状与β-内啡肽的关系：两种亚型。

Symptoms of premenstrual syndrome as a function of beta-endorphin: two subtypes.

Giannini A J, Melemis S M, Martin D M, Folts D J

Department of Psychiatry, Ohio State University, Columbus.

Prog Neuropsychopharmacol Biol Psychiatry. 1994 Mar;18(2):321-7. doi: 10.1016/0278-5846(94)90063-9.

Abstract

Forty six women presenting with symptoms of premenstrual syndrome (PMS) were studied. Ages ranged from 21 to 32. All women answered a questionnaire based on DSM-III-R criteria. They then had serum beta-endorphin levels drawn on day 1 and day 20 of their menstrual Cycle. 2. Beta-endorphin levels were compared with symptom presentation. Such symptoms as anxiety, food cravings and physical discomfort were associated with significant decline in beta-endorphin. Other symptoms were found equally distributed in both groups. The existence or absence of beta-endorphin decline in specific PMS subgroup was postulated.

摘要

对46名出现经前综合征（PMS）症状的女性进行了研究。年龄在21岁至32岁之间。所有女性都根据《精神疾病诊断与统计手册》第三版修订版（DSM-III-R）标准回答了一份问卷。然后，她们在月经周期的第1天和第20天进行了血清β-内啡肽水平检测。2. 将β-内啡肽水平与症状表现进行了比较。焦虑、食物渴望和身体不适等症状与β-内啡肽的显著下降有关。其他症状在两组中分布均匀。推测了特定经前综合征亚组中β-内啡肽下降的存在与否。