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类风湿性关节炎中的颈椎融合术:长期随访

Cervical spine arthrodesis in rheumatoid arthritis: a long-term follow-up.

作者信息

Krieg J C, Clark C R, Goetz D D

机构信息

Department of Orthopaedic Surgery, University of Iowa Hospitals and Clinics, Iowa City 52242.

出版信息

Yale J Biol Med. 1993 May-Jun;66(3):257-62.

Abstract

Forty-one patients with rheumatoid arthritis involving the cervical spine had a posterior cervical arthrodesis. They were followed for a minimum period of seven years. The diagnoses prior to surgery included cranial settling, atlantoaxial subluxation, subaxial subluxation, and any combination of these three. All patients had posterior arthrodesis, with or without methylmethacrylate, and iliac crest autogenous bone graft. In addition, one patient had an anterior vertebrectomy, and two had transoral resection of the odontoid. Follow-up consisted of a subjective questionnaire, standard radiographs, and physical examination, including a neurologic exam. This information was compared to preoperative data available in the patient's medical record, postoperative data, and the information obtained in a similar study undertaken in 1987. At the time of follow-up, thirteen patients were known to be dead. One patient could not be located. Of the remaining twenty-six patients, eighteen underwent the full examination, including physical exam and radiographs. The remaining nine patients were contacted and interviewed, but were unavailable for exam and radiographs. All patients considered the operation a success. Only one patient at follow-up had a non-union. This was stable over time. No patient had a deterioration in neurologic function. There was no significant degeneration or instability seen at levels adjacent to the fused segments as compared to the rest of the cervical spine. Posterior cervical spine arthrodesis for rheumatoid involvement of the neck is a safe, efficacious procedure with no significant deterioration of effects over time.

摘要

41例颈椎受累的类风湿关节炎患者接受了颈椎后路融合术。他们至少随访了7年。手术前的诊断包括颅骨沉降、寰枢椎半脱位、下颈椎半脱位以及这三种情况的任意组合。所有患者均接受了后路融合术,使用或未使用甲基丙烯酸甲酯,并进行了髂嵴自体骨移植。此外,1例患者接受了前路椎体切除术,2例患者接受了经口齿状突切除术。随访包括主观问卷调查、标准X线片以及体格检查,包括神经学检查。将这些信息与患者病历中的术前数据、术后数据以及1987年进行的一项类似研究中获得的信息进行比较。在随访时,已知13例患者死亡。1例患者无法找到。其余26例患者中,18例接受了全面检查,包括体格检查和X线片检查。其余9例患者接受了联系和访谈,但无法进行检查和拍摄X线片。所有患者均认为手术成功。随访时只有1例患者出现不愈合。随着时间推移,情况稳定。没有患者出现神经功能恶化。与颈椎其余部分相比,融合节段相邻节段未出现明显退变或不稳定。颈椎后路融合术治疗颈部类风湿关节炎累及是一种安全、有效的手术,随着时间推移效果无明显恶化。

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