Okayasu I, Hara Y, Nakamura K, Rose N R
Department of Pathology, School of Medicine, Tokyo Medical and Dental University, Japan.
Am J Clin Pathol. 1994 Jun;101(6):698-702. doi: 10.1093/ajcp/101.6.698.
To determine possible racial and age-related differences of focal autoimmune thyroiditis between white and black Americans, autopsy material from American subjects was evaluated for incidence and severity of chronic lymphocytic thyroiditis. The overall incidence of lymphocytic infiltration in thyroid sections from subjects aged more than 20 years was 41.4% in white females, 20% in white males, 17.4% in black females, and 8.5% in black males. An increase to 54.8% in incidence of thyroiditis from the first decade onward was noted in white females older than 80 years of age. Age did not cause a remarkable increase in incidence of thyroiditis in white males, in black females, or black males. The susceptibility to chronic thyroiditis in American white males and females was almost the same as that of British white males and females. The incidence of thyroiditis in black females and males was similar to that in Japanese females and males. These findings showed clear racial differences in susceptibility to chronic thyroiditis.
为了确定美国白人和黑人之间局灶性自身免疫性甲状腺炎可能存在的种族和年龄相关差异，对来自美国受试者的尸检材料进行了评估，以了解慢性淋巴细胞性甲状腺炎的发病率和严重程度。20岁以上受试者甲状腺切片中淋巴细胞浸润的总体发生率在白人女性中为41.4%，白人男性中为20%，黑人女性中为17.4%，黑人男性中为8.5%。80岁以上的白人女性从第一个十年起甲状腺炎发病率增至54.8%。年龄在白人男性、黑人女性或黑人男性中并未导致甲状腺炎发病率显著增加。美国白人男性和女性对慢性甲状腺炎的易感性与英国白人男性和女性几乎相同。黑人女性和男性的甲状腺炎发病率与日本女性和男性相似。这些发现表明在慢性甲状腺炎易感性方面存在明显的种族差异。
