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桥本甲状腺炎的营养管理。

Nutritional Management of Thyroiditis of Hashimoto.

机构信息

Department of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.

Department of Clinical Immunology, University Hospital Lozenetsz, Sofia University St. Kliement Ohridski, 1 "Kozyak" St., 1407 Sofia, Bulgaria.

出版信息

Int J Mol Sci. 2022 May 5;23(9):5144. doi: 10.3390/ijms23095144.

Abstract

Since the thyroid gland is one of the organs most affected by autoimmune processes, many patients with thyroiditis of Hashimoto (TH) seek medical advice on lifestyle variance and dietary modifications to improve and maintain their hyroid function. In this review, we aim to present and discuss some challenges associated with the nutritional management of TH, focusing on environmental and dietary deficits, inflammatory and toxic nutrients, cyanotoxins, etc. We discuss the relationships among different diets, chronic inflammation, and microbiota, and their impact on the development and exacerbation of TH in detail. We share some novel insights into the role of vitamin D and melatonin for preserving thyroid function during chronic inflammation in autoimmune predisposed subjects. A comprehensive overview is provided on anti-inflammatory nutrients and ecological diets, including foods for cleansing and detoxification, which represent strategies to prevent relapses and achieve overall improvement of life quality. In conclusion, data from biomedical and clinical studies provide evidence that an appropriate dietary and lighting regimen could significantly improve the function of the thyroid gland and reduce the reactivity of autoantibodies in TH. Compliance with nutritional guidelines may help TH patients to reduce the need for medicines.

摘要

由于甲状腺是受自身免疫过程影响最严重的器官之一,许多桥本甲状腺炎(TH)患者寻求医疗建议,了解生活方式的差异和饮食调整,以改善和维持甲状腺功能。在这篇综述中,我们旨在介绍和讨论与 TH 的营养管理相关的一些挑战,重点关注环境和饮食缺陷、炎症和毒性营养素、蓝藻毒素等。我们详细讨论了不同饮食、慢性炎症和微生物群之间的关系,以及它们对 TH 的发展和恶化的影响。我们分享了一些关于维生素 D 和褪黑素在自身免疫倾向个体的慢性炎症期间维持甲状腺功能的新见解。我们全面概述了抗炎营养素和生态饮食,包括清洁和排毒食品,这些都是预防复发和实现整体生活质量提高的策略。总之,来自生物医学和临床研究的数据提供了证据,表明适当的饮食和光照方案可以显著改善甲状腺功能,并降低 TH 中自身抗体的反应性。遵守营养指南可能有助于 TH 患者减少对药物的需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2c6/9101513/0cda16be697c/ijms-23-05144-g001.jpg

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