Ito M, Hayashi K, Yamada M, Uetani M, Nakamura T
Department of Radiology, Nagasaki University School of Medicine, Japan.
Radiology. 1993 Nov;189(2):497-502. doi: 10.1148/radiology.189.2.8210380.
To investigate the relationship of spinal osteophytes to vertebral bone mineral density (BMD) and to spinal fracture.
This relationship was investigated in 203 men. Integral BMD was measured with dual x-ray absorptiometry, and both cortical and trabecular BMD were measured with quantitative computed tomography (QCT).
Trabecular BMD was found to decrease with age in subjects with and without large osteophytes, while cortical and integral BMD decreased with age only in subjects without large osteophytes. Trabecular BMD in men without fracture was significantly higher than in those with fracture (P < .05 for BMD measured with single-energy QCT), while there was no significant difference between these groups in cortical or integral BMD.
Measurement of trabecular BMD with QCT provides information useful in detection of age-related bone loss and of fracture in men with and without osteophytes.
研究脊柱骨赘与椎体骨密度（BMD）及脊柱骨折之间的关系。
对203名男性进行了此项关系的研究。采用双能X线吸收法测量整体骨密度，并用定量计算机断层扫描（QCT）测量皮质骨和小梁骨的骨密度。
在有和没有大骨赘的受试者中，小梁骨密度均随年龄增长而降低，而皮质骨和整体骨密度仅在没有大骨赘的受试者中随年龄增长而降低。未发生骨折男性的小梁骨密度显著高于发生骨折的男性（单能QCT测量的骨密度P < 0.05），而两组间皮质骨或整体骨密度无显著差异。
用QCT测量小梁骨密度可为检测有无骨赘男性的年龄相关性骨质流失及骨折提供有用信息。
