Schwizer W, Borovicka J, Fried M, Inauen W
Policlinique médicale universitaire (PMU), Lausanne.
Schweiz Med Wochenschr Suppl. 1993;54:8-14.
Esophageal diseases frequently cause symptoms such as heartburn, epigastric pain and dysphagia. This article discusses the indications, techniques and limitations of currently available diagnostic procedures. Investigation of symptoms should proceed in a logical stepwise manner, beginning with endoscopy to exclude esophagitis or neoplasia. Symptoms due to acid reflux can be identified by 24h esophageal pH-metry to document a temporal association between symptoms and episodes of esophageal acidification. Stationary or ambulatory manometric recording of esophageal pressures can be used to diagnose esophageal motor disorders such as achalasia, nutcracker esophagus, diffuse esophageal spasm, or dysfunction of the upper or lower esophageal sphincter. Combined 24 h pH-manometry should be used to test the temporal association between pain, reflux, or abnormal motility in patients with non-cardiac chest pain. Video-fluoroscopy is the most appropriate technique to diagnose swallowing disorders. Pulmonary aspiration of gastro-esophageal reflux can be documented with scintigraphy.
食管疾病常引发烧心、上腹部疼痛和吞咽困难等症状。本文讨论了当前可用诊断程序的适应症、技术及局限性。对症状的检查应按逻辑逐步进行,首先进行内镜检查以排除食管炎或肿瘤。通过24小时食管pH监测可识别因酸反流引起的症状,以记录症状与食管酸化发作之间的时间关联。食管压力的静态或动态测压记录可用于诊断食管运动障碍,如贲门失弛缓症、胡桃夹食管、弥漫性食管痉挛或食管上、下括约肌功能障碍。对于非心源性胸痛患者,应采用联合24小时pH测压法来检测疼痛、反流或异常运动之间的时间关联。视频荧光检查是诊断吞咽障碍的最合适技术。胃食管反流的肺吸入情况可用闪烁扫描法记录。