[The role of lipid peroxides and blood rheological disorders in the pathogenesis and clinical course of ischemic heart disease].

Combined assessment of primary and secondary products of lipid peroxidation, functional activity of red cells has been conducted in 130 patients with ischemic heart disease running different courses. Lipid peroxidation was found enhanced both in the whole blood and red blood cells. Blood rheology got abnormal. It is shown that lipid peroxides are involved in damaging erythrocytic membrane structure and function, thus promoting the progression of ischemic heart disease.