Kilpe V E, Krakauer H, Wren R E
Bureau of Policy Development, Health Care Financing Administration, Baltimore, Maryland 21207.
Transplantation. 1993 Sep;56(3):554-61. doi: 10.1097/00007890-199309000-00012.
Analysis of 5180 liver transplant cases from 37 liver transplant centers in the United States (1982-1991) shows an overall one-year survival rate of 79.4 +/- 0.6% and a five-year survival rate of 69.2 +/- 0.9%. There was marked improvement in the one-year survival rate after liver transplantation from 36.0 +/- 9.6% in 1982 to 85.0 +/- 1.8% in 1991. One-year survival rates after liver transplantation for postnecrotic cirrhosis, primary biliary cirrhosis, alcoholic cirrhosis, primary sclerosing cholangitis, alpha-1-antitrypsin deficiency, and Wilson's disease ranged from 78.4 +/- 1.0% to 84.2 +/- 1.5% and five-year survival rates from 68.6 +/- 3.8% to 79.2 +/- 5.3%. Survival rates after liver transplantation for hemochromatosis were poor--a one-year survival rate of 53.8 +/- 6.8% and a five year survival rate of 43.1 +/- 11%. One- and five-year survival rates for the 0-13 years age group were 74.6 +/- 2.8% and 66.7 +/- 3.4%; for the 14-37 years age group, 83.3 +/- 1.2% and 73.8 +/- 1.8%; for the 38-54 years age group, 79.6 +/- 0.8% and 69.7 +/- 1.3%; for the 55-63 years age group, 76.0 +/- 1.4% and 63.0 +/- 3.1%; and for the 64-77 years age group, 76.5 +/- 3.0% and 65.4 +/- 4.6%.
对美国37个肝移植中心1982年至1991年期间的5180例肝移植病例进行分析，结果显示总体一年生存率为79.4±0.6%，五年生存率为69.2±0.9%。肝移植后的一年生存率有显著提高，从1982年的36.0±9.6%提高到1991年的85.0±1.8%。坏死后性肝硬化、原发性胆汁性肝硬化、酒精性肝硬化、原发性硬化性胆管炎、α-1抗胰蛋白酶缺乏症和威尔逊病肝移植后的一年生存率在78.4±1.0%至84.2±1.5%之间，五年生存率在68.6±3.8%至79.2±5.3%之间。血色素沉着症肝移植后的生存率较低，一年生存率为53.8±6.8%，五年生存率为43.1±11%。0至13岁年龄组的一年和五年生存率分别为74.6±2.8%和66.7±3.4%；14至37岁年龄组为83.3±1.2%和73.8±1.8%；38至54岁年龄组为79.6±0.8%和69.7±1.3%；55至63岁年龄组为76.0±1.4%和63.0±3.1%；64至77岁年龄组为76.5±3.0%和65.4±4.6%。
