一种异常的Rh血型表型，提示Cw抗原的异质性。
An unusual Rh phenotype indicating heterogeneity of the Cw antigen.
作者信息
Habibi B, André J, Fouillade M T, Lopez M, Salmon C
出版信息
Vox Sang. 1976;31(2):103-8. doi: 10.1111/j.1423-0410.1976.tb02195.x.
A family is reported in which a new Cw antigen occurred in two generations. This was recognized by 17 anti-Cw sera, but by none of the 21 anti-C sera which were, however, shown to react strongly with common Cw+ cells. This unusual finding provides evidence that the Cw antigen is in fact heterogeneous. On the basis of data obtained from absorption-elution and coagglutination studies a tentative explanation is attempted: common Cw+ phenotypes are assumed to be Cw (+1+2) and the present phenotype Cw (+1-2). Anti-Cw sera should accordingly be anti-Cw1, whereas anti-C sera should only react with Cw2.
据报道，有一个家族中两代人出现了一种新的Cw抗原。17份抗Cw血清识别出了这种抗原，但21份抗C血清均未识别出，不过这些抗C血清与常见的Cw阳性细胞反应强烈。这一不寻常的发现证明Cw抗原实际上是异质性的。基于吸收-洗脱和协同凝集研究获得的数据，尝试给出一个初步解释：常见的Cw阳性表型被认为是Cw（+1+2），而目前的表型是Cw（+1-2）。因此，抗Cw血清应为抗Cw1，而抗C血清应仅与Cw2反应。
Zotero 插件