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重度糖尿病酮症酸中毒的多种并发症。文献综述

Multiple complications in severe diabetic ketoacidosis. A short review of the literature.

作者信息

Clarke B F, Campbell I W

出版信息

Acta Diabetol Lat. 1975 Sep-Dec;12(5-6):327-37. doi: 10.1007/BF02581105.

DOI:10.1007/BF02581105
PMID:821284
Abstract

Diabetic ketoacidosis may be associated with a wide variety of complications, some of which are uncommon and not widely appreciated. A case of severe ketoacidosis with multiple complications including septicaemia, pneumomediastinum, gastro-intestinal haemorrhage, magnesium depletion and multiple mononeuropathy is reported in a 17-year old girl who made a successful recovery. The patient had not taken insulin for almost 4 days, had no preceding illness and was admitted in a near moribund state with hypothermia (34.2 degrees C), hypotension (80/50) and an arterial pH less than 6.8. There was a leukocytosis 41,200, the blood culture grew haemolytic streptococci and chest radiology showed pneumomediastinum. I.v. therapy was continued for some days and the patient developed clinical features of magnesium depletion. During the recovery period she developed multiple mononeuropathy. A brief review of these complications is given.

摘要

糖尿病酮症酸中毒可能与多种并发症相关,其中一些并发症并不常见,也未得到广泛认识。本文报告了一名17岁女孩的严重酮症酸中毒病例,该病例伴有多种并发症,包括败血症、纵隔气肿、胃肠道出血、镁缺乏和多发性单神经病,患者最终成功康复。该患者近4天未注射胰岛素,无前驱疾病,入院时处于濒死状态,体温过低(34.2摄氏度)、低血压(80/50),动脉血pH值低于6.8。白细胞计数为41,200,血培养发现溶血性链球菌,胸部放射学检查显示纵隔气肿。静脉治疗持续了数天,患者出现了镁缺乏的临床症状。在康复期间,她患上了多发性单神经病。本文对这些并发症进行了简要综述。

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The value of continuous ECG monitoring during treatment of diabetic ketoacidosis. A computer study.糖尿病酮症酸中毒治疗期间连续心电图监测的价值。一项计算机研究。
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本文引用的文献

1
Neuropathy in Children with Diabetes Mellitus.糖尿病患儿的神经病变
Br Med J. 1963 Mar 23;1(5333):784-5. doi: 10.1136/bmj.1.5333.784.
2
Fatal Diabetic Ketosis.致命性糖尿病酮症
Br Med J. 1961 Jan 28;1(5221):247-50. doi: 10.1136/bmj.1.5221.247.
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Metabolic studies in diabetic coma.糖尿病昏迷的代谢研究。
Trans Assoc Am Physicians. 1947;60(1 vol):102-9.
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SERUM POTASSIUM, MAGNESIUM, AND CALCIUM LEVELS IN DIABETIC ACIDOSIS.糖尿病酮症酸中毒患者的血清钾、镁和钙水平
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5
ON DIABETIC ACIDOSIS: A Detailed Study of Electrolyte Balances Following the Withdrawal and Reestablishment of Insulin Therapy.论糖尿病酸中毒:胰岛素治疗停用及恢复后电解质平衡的详细研究
J Clin Invest. 1933 Mar;12(2):297-326. doi: 10.1172/JCI100504.
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Multiple symmetric bilateral cranial nerve palsies in patients with unregulated diabetes mellitus; report of three cases.未控制的糖尿病患者出现多发性对称性双侧颅神经麻痹;三例报告。
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Metabolic studies in severe diabetic ketosis.重度糖尿病酮症的代谢研究
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Diabetic coma.
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Studies of the resistance to infection in diabetes mellitus: local exudative cellular response.糖尿病感染抵抗力的研究:局部渗出性细胞反应。
J Lab Clin Med. 1962 Jun;59:1008-15.
10
Autogenous mono-neuropathy: diagnosis, treatment and clinical significance.自体单神经病:诊断、治疗及临床意义
Med Clin North Am. 1960 Jul;44:989-99. doi: 10.1016/s0025-7125(16)33985-2.