Shapovalova K B, Pominova E V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1993 Jul-Aug;43(4):800-7.
In experiments with 57 Sprague-Dawley male rats was studied the influence of single right- and left-side injections of different doses of choline agonist carbachol and choline blocker scopolamine into the dorsal part of the neostriatum (the head of the caudate nucleus) on active avoidance conditioning in a T-maze and on the locomotor activity. Non-adequately high carbachol doses disturbed the process of conditioning during the whole training period inducing no significant changes in locomotor activity of the rats. Microinjections of carbachol and scopolamine in small doses did not change the process of T-maze conditioning and also did not influence the dynamics and the level of locomotor activity of the experimental rats in comparison with the control ones.
在对57只斯普拉格-道利雄性大鼠进行的实验中，研究了向新纹状体背侧（尾状核头部）单次右侧和左侧注射不同剂量的胆碱激动剂卡巴胆碱和胆碱阻断剂东莨菪碱对T迷宫中主动回避条件反射和运动活动的影响。剂量过高的卡巴胆碱在整个训练期间干扰了条件反射过程，但对大鼠的运动活动没有显著影响。与对照组相比，小剂量注射卡巴胆碱和东莨菪碱并未改变T迷宫条件反射过程，也未影响实验大鼠运动活动的动态变化和水平。
