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酿酒酵母二号染色体4.3 kb片段的序列与功能分析，该片段包含三个开放阅读框。

Sequence and function analysis of a 4.3 kb fragment of Saccharomyces cerevisiae chromosome II including three open reading frames.

作者信息

Schaaff-Gerstenschläger I, Baur A, Boles E, Zimmermann F K

机构信息

Institut für Mikrobiologie, TH Darmstadt, Germany.

出版信息

Yeast. 1993 Aug;9(8):915-21. doi: 10.1002/yea.320090811.

DOI:10.1002/yea.320090811
PMID:8212898
Abstract

The nucleotide sequence of a fragment of 4337 base pairs of Saccharomyces cerevisiae chromosome II has been determined. The sequence contains three open reading frames, one of them being incomplete. Deletion analysis showed that YBR12.31 is essential for yeast growth, while deletion mutants of YBR12.32 and YBR12.33 are viable. YBR12.33 is identical to SMY2, isolated as a suppressor of a myo2 mutant (Lillie, S.H. and Brown, S.S., unpublished, EMBL M90654).

摘要

已测定酿酒酵母二号染色体上一段4337个碱基对片段的核苷酸序列。该序列包含三个开放阅读框，其中一个不完整。缺失分析表明，YBR12.31对酵母生长至关重要，而YBR12.32和YBR12.33的缺失突变体是可行的。YBR12.33与作为肌球蛋白2突变体（Lillie，S.H.和Brown，S.S.，未发表，EMBL M90654）的抑制子分离得到的SMY2相同。

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引用本文的文献

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Genome Res. 1998 Oct;8(10):1060-73. doi: 10.1101/gr.8.10.1060.
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Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.核转运缺陷和核膜改变与酿酒酵母NPL4基因的突变有关。
Mol Biol Cell. 1996 Nov;7(11):1835-55. doi: 10.1091/mbc.7.11.1835.
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Complete DNA sequence of yeast chromosome II.
酵母二号染色体的完整DNA序列。
EMBO J. 1994 Dec 15;13(24):5795-809. doi: 10.1002/j.1460-2075.1994.tb06923.x.