Jensen-Waern M, Nyberg L
Department of Medicine and Surgery, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala.
Zentralbl Veterinarmed A. 1993 Jun;40(5):321-7. doi: 10.1111/j.1439-0442.1993.tb00634.x.
Various markers for stress were evaluated in the plasma of pigs. Treadmill exercise was chosen as a well defined and quantifiable stressor. One group of non-stress-susceptible pigs had to carry out two intense exercise bouts at a one-week interval, and another group remained in their pens and served as controls. Large interindividual differences in the performance and in the hormonal and metabolic responses to exercise were observed. The exercise stress resulted in an immediate increase in the plasma concentrations of cortisol, lactate and hypoxanthine, with a return to the pre-exercise levels within one hour. No direct effect of physical stress on CBG binding capacity or on the concentrations of xanthine and uric acid was observed. In two very nervous pigs, even mild stress in connection with the first blood sampling resulted in an elevated concentration of lactate, but the cortisol and hypoxanthine values remained at the basal level. It is concluded that plasma concentrations of cortisol, lactate and hypoxanthine are valuable markers for physical stress.
对猪血浆中的各种应激标志物进行了评估。选择跑步机运动作为一种明确且可量化的应激源。一组不易受应激影响的猪必须每隔一周进行两次高强度运动，另一组则留在栏内作为对照。观察到在运动表现以及激素和代谢反应方面存在较大的个体差异。运动应激导致血浆皮质醇、乳酸和次黄嘌呤浓度立即升高，一小时内恢复到运动前水平。未观察到身体应激对皮质类固醇结合球蛋白结合能力或黄嘌呤和尿酸浓度有直接影响。在两只非常神经质的猪中，即使与首次采血相关的轻度应激也导致乳酸浓度升高，但皮质醇和次黄嘌呤值仍保持在基础水平。结论是，血浆皮质醇、乳酸和次黄嘌呤浓度是身体应激的有价值标志物。
