Hiller A, Pyykkö I, Saarnivaara L
Department of Anaesthesia, Otolaryngological Hospital, Helsinki, Finland.
Acta Anaesthesiol Scand. 1993 Aug;37(6):556-61. doi: 10.1111/j.1399-6576.1993.tb03764.x.
Simple clinical tests, like Romberg's test or a walking test, have proved to be inadequate guidelines for safe discharge after outpatient anaesthesia. A randomised study was therefore planned to compare postural stability measured by computerised posturography in 31 oral midazolam-atropine premedicated children aged 6.9 (s.e. 0.4) years who had been anaesthetised with either propofol/alfentanil/N2O or thiopentone/halothane/N2O. The sway velocity of the children was measured before premedication and 1, 2 and 3 h after the end of anaesthesia. Results show that sway velocity had returned to baseline values 3 h after the end of anaesthesia in all children who had received propofol/alfentanil/N2O and in 12 of the 15 children who had received thiopentone/halothane/N2O. The quantified version of the Romberg test performed with eyes open or closed was not impaired after anaesthesia, compared with the control values, indicating that in children poor equilibrium is not compensated by vision. The clinical recovery with respect to the times to eye opening, to responding to command or to being fully awake did not differ between the two anaesthesia methods. On the basis of recovery assessed by postural stability, propofol/alfentanil/N2O anaesthesia was not preferable to thiopentone/halothane/N2O anaesthesia after minor paediatric otolaryngological surgery.
简单的临床测试,如闭目直立试验或步行测试,已被证明不足以作为门诊麻醉后安全出院的指导标准。因此,开展了一项随机研究,比较31名年龄为6.9(标准误0.4)岁、术前使用口服咪达唑仑和阿托品的儿童在接受丙泊酚/阿芬太尼/氧化亚氮或硫喷妥钠/氟烷/氧化亚氮麻醉后,通过计算机化姿势描记法测量的姿势稳定性。在术前用药前以及麻醉结束后1、2和3小时测量儿童的摇摆速度。结果显示,在所有接受丙泊酚/阿芬太尼/氧化亚氮麻醉的儿童以及15名接受硫喷妥钠/氟烷/氧化亚氮麻醉的儿童中的12名中,摇摆速度在麻醉结束后3小时恢复到基线值。与对照值相比,麻醉后进行的睁眼或闭眼量化版闭目直立试验未受影响,这表明在儿童中,视力无法补偿平衡能力差的问题。两种麻醉方法在睁眼时间、对指令做出反应的时间或完全清醒的时间方面的临床恢复情况没有差异。基于姿势稳定性评估的恢复情况,小儿耳鼻喉科小手术后,丙泊酚/阿芬太尼/氧化亚氮麻醉并不优于硫喷妥钠/氟烷/氧化亚氮麻醉。