Youssef H A, Kinsella A, Waddington J L
St. Davnet's Hospital, Monaghan, Ireland.
Acta Psychiatr Scand. 1993 Aug;88(2):135-9. doi: 10.1111/j.1600-0447.1993.tb03427.x.
The morbid risk for schizophrenia was determined separately for men and women within each of 36 contiguous district electoral divisions of a rural Irish county in which all cases of schizophrenia satisfying DSM-III-R criteria had been sought. The distribution of morbid risk values for men (0.0-19.2 per 1000) was in accordance with a statistical model for random occurrences in space, while for women (0.0-38.3 per 1000) it deviated markedly from such a model; thus, morbid risk for schizophrenia showed very prominent geographical variations in women, but not in men. These findings may have a basis in factors that can show both spatial inhomogeneity and gender specificity in their consequences for schizophrenia.
在爱尔兰一个乡村县的36个相邻选区中,分别确定了男性和女性患精神分裂症的患病风险。在这些选区中,已对所有符合《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)标准的精神分裂症病例进行了排查。男性的患病风险值分布(每1000人中有0.0 - 19.2例)符合空间随机发生的统计模型,而女性的患病风险值分布(每1000人中有0.0 - 38.3例)则明显偏离该模型;因此,精神分裂症的患病风险在女性中呈现出非常显著的地理差异,而在男性中则没有。这些发现可能基于一些因素,这些因素在对精神分裂症的影响方面既表现出空间不均匀性,又具有性别特异性。