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麸皮和消胆胺对猴子血脂的影响。

Effect of bran and cholestyramine on plasma lipids in monkeys.

作者信息

Malinow M R, McLaughlin P, Papworth L, Naito H K, Lewis L A

出版信息

Am J Clin Nutr. 1976 Aug;29(8):905-11. doi: 10.1093/ajcn/29.8.905.

DOI:10.1093/ajcn/29.8.905
PMID:821335
Abstract

Semipurified diets whose cholesterol content varied from 34 to 120 mg/100 kcal were given to adult female cynomolgus monkeys (Macaca fascicularis) for 9 months. The intake of dietary fiber was increased through the addition of wheat, rice, or soya bran; 5% cholestyramine was given to one group of monkeys. None of the brans reduced plasma levels of cholesterol, whereas cholestyramine produced marked hypocholesterolemic effects. Triglyceride levels increased with higher cholesterol intake, but no additional changes were induced by any of the experimental diets. Plasma phospholipids were reduced by cholestyramine.

摘要

将胆固醇含量在34至120毫克/100千卡之间变化的半纯化饮食喂给成年雌性食蟹猴(猕猴)9个月。通过添加小麦、大米或大豆麸皮来增加膳食纤维的摄入量;给一组猴子喂食5%的消胆胺。没有一种麸皮能降低血浆胆固醇水平,而消胆胺则产生了显著的降胆固醇作用。甘油三酯水平随着胆固醇摄入量的增加而升高,但任何一种实验饮食都没有引起额外的变化。消胆胺可降低血浆磷脂水平。

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1
Effect of bran and cholestyramine on plasma lipids in monkeys.麸皮和消胆胺对猴子血脂的影响。
Am J Clin Nutr. 1976 Aug;29(8):905-11. doi: 10.1093/ajcn/29.8.905.
2
Treatment of established atherosclerosis during cholesterol feeding in monkeys.
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Lipid changes in atherosclerotic aortas of Macaca fascicularis after various regression regimens.
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Hypolipidaemic principle of the husk and bran of paddy. Nature of the substance and its effect on cholesterol absorption and faecal bile salt excretion in rats fed a high-fat-high-cholesterol diet.稻谷外壳及麸皮的降血脂原理。该物质的性质及其对高脂高胆固醇饮食喂养大鼠胆固醇吸收和粪便胆汁盐排泄的影响。
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