碘-125治疗甲状腺毒症后发生的喉恶性肿瘤。

Laryngeal malignancy following iodine-125 therapy for thyrotoxicosis.

作者信息

McKillop J H, Doig J A, Kennedy J S, Thomson J A, Greig W R

出版信息

Lancet. 1978 Dec 2;2(8101):1177-9. doi: 10.1016/s0140-6736(78)92158-x.

Abstract

A 52-year-old woman presented with a laryngeal sarcoma eight years after receiving two doses, each of 30 mCi, of iodine-125 for thyrotoxicosis. That extrathyroidal tissue receives a higher radiation dose of low-energy photon radiation from iodine-125 than from an equivalent microcurie dose of iodine-131 and that the tumour was of a type which rarely arises spontaneously in the larynx suggest a possible link between the development of the tumour and iodine-125 therapy.

摘要

一名52岁女性在接受两次剂量均为30毫居里的碘-125治疗甲状腺毒症八年后，出现了喉部肉瘤。甲状腺外组织从碘-125接受的低能光子辐射剂量高于同等微居里剂量的碘-131，且该肿瘤是一种在喉部很少自发出现的类型，这表明肿瘤的发生与碘-125治疗之间可能存在联系。