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[心肌血运重建手术早期术后并发症中的心肌梗死:发生率、临床研究及机制]

[Myocardial infarction in early postoperative complications in operations of myocardial revascularization: incidences, clinical study and mechanisms].

作者信息

Delaye J, Mikaeloff P, Chassignole J, Freillat A, Janin A, Estanove J, Dugres B, Gonin A

出版信息

Arch Mal Coeur Vaiss. 1976 Jul;69(7):701-10.

PMID:821441
Abstract

A study of the electrocardiograms and enzyme levels after surgery to revascularise the myocardium in a group of 174 consecutive patients has allowed us to demonstrate 19 cases of early postoperative myocardial infarction (EPOMI) (10.9%). 10 of these cases had no clinical features of EPOMI; 9 had clinical signs (collapse of altered systemic pressures, arrhythmias) or haemodynamic disorders (raised left atrial pressure). The EPOMI turned out to be fatal in 3 cases (19%), and to be complicated by left ventricular failure in 6 cases (32%). Post-operative coronary arteriography showed that 8 out of 20 grafts were occluded in 13 patients; ventriculography showed the myocardial damage consequent upon EPOMI in 8 patients out of 12; Autopsy showed graft occlusion in each of the two patients. The means of diagnosis of EPOMI must be electrocardiographic and enzymatic. An attempt has been made to study the causes of EPOMI: aortocoronary bypass hazardous because of poor distal supply (6 cases) or surgical difficulties (6 cases); progression of the atheromatous lesions (3 cases); infarct already inicipient at the time of surgery (1 case). EPOMI is a complication of cardiac surgery which must be recognised; the mechanisms are diverse, and any of the factors which are relevant to the surgical procedure may be a cause.

摘要

对一组连续174例接受心肌血运重建手术患者术后的心电图和酶水平进行研究后,我们发现了19例术后早期心肌梗死(EPOMI)(10.9%)。其中10例无EPOMI的临床特征;9例有临床体征(全身压力改变导致的虚脱、心律失常)或血流动力学紊乱(左心房压力升高)。EPOMI在3例(19%)中导致死亡,在6例(32%)中并发左心室衰竭。术后冠状动脉造影显示,13例患者中20条移植血管有8条闭塞;心室造影显示12例患者中有8例因EPOMI导致心肌损伤;尸检显示2例患者均有移植血管闭塞。EPOMI的诊断方法必须是心电图和酶学检查。已尝试研究EPOMI的病因:由于远端供血不足(6例)或手术困难(6例)导致主动脉冠状动脉搭桥术危险;动脉粥样硬化病变进展(3例);手术时已存在早期梗死(1例)。EPOMI是心脏手术的一种并发症,必须予以识别;其机制多种多样,与手术操作相关的任何因素都可能是病因。

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