Mazzucotelli J P, Baufreton C, Duval A M, Deleuze P, Hillion M L, Loisance D, Cachera J P
Service de chirurgie cardiaque, hôpital Henri-Mondor, Créteil.
Arch Mal Coeur Vaiss. 1993 Mar;86(3):321-7.
The aim of this study was to evaluate the status of the native aortic valve in patients operated for acute dissection of the ascending. aorta (ADAA). Between November 1972 and November 1991, 93 patients were operated for ADAA. There were 76 men and 17 women (average age 54 +/- 12 years). The aortic valve was reserved in 80 cases (86%). In 13 patients (14%) aortic valve replacement was associated with replacement of the ascending aorta. The early mortality was 29% (27/93). The global actuarial survival rates at 5, 10 and 15 years were 60.2 +/- 5.2%, 49.7 +/- 6.1% and 26.9 +/- 9.9% respectively. Fifty patients (94%) in whom the native aortic valve was preserved were followed up. Nine patients (18%) died and average of 97 +/- 46 months after surgery. The causes of death were aortic rupture or extension of the dissection (N = 4), ischemic cardiac failure (N = 2), renal failure (N = 1), cerebrovascular accident (N = 1) and sudden death (N = 1). Forty one patients underwent transthoracic echocardiography. Seven patients developed severe aortic regurgitation, 6 of whom had to be reoperated for aortic valve replacement. Echocardiography showed absence of of minimal aortic regurgitation in 22 cases and mild aortic regurgitation with normal left ventricular function in 12 cases (in 2 cases, aortic valve replacement was associated with surgical treatment of another valvular lesion or of coronary artery disease). Therefore, aortic valve replacement was performed in 8 patients 61.5 +/- 51.2 months after the initial operation.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究旨在评估升主动脉急性夹层(ADAA)手术患者的自体主动脉瓣状况。1972年11月至1991年11月期间,93例患者接受了ADAA手术。其中男性76例,女性17例(平均年龄54±12岁)。80例(86%)保留了主动脉瓣。13例(14%)患者在升主动脉置换的同时进行了主动脉瓣置换。早期死亡率为29%(27/93)。5年、10年和15年的总体精算生存率分别为60.2±5.2%、49.7±6.1%和26.9±9.9%。对50例(94%)保留自体主动脉瓣的患者进行了随访。9例(18%)患者在术后平均97±46个月死亡。死亡原因包括主动脉破裂或夹层扩展(4例)、缺血性心力衰竭(2例)、肾衰竭(1例)、脑血管意外(1例)和猝死(1例)。41例患者接受了经胸超声心动图检查。7例患者出现严重主动脉瓣反流,其中6例因主动脉瓣置换而再次手术。超声心动图显示,22例患者无或仅有轻微主动脉瓣反流,12例患者有轻度主动脉瓣反流且左心室功能正常(2例患者在主动脉瓣置换的同时还接受了其他瓣膜病变或冠状动脉疾病的手术治疗)。因此,8例患者在初次手术后61.5±51.2个月进行了主动脉瓣置换。(摘要截选至250词)