Mazzucotelli J P, Deleuze P H, Baufreton C, Duval A M, Hillion M L, Loisance D Y, Cachera J P
Department of Cardiac and Thoracic Surgery, Hôpital Henri Mondor, Créteil, France.
Ann Thorac Surg. 1993 Jun;55(6):1513-7. doi: 10.1016/0003-4975(93)91100-2.
The aim of the present study was to determine the long-term status of the native aortic valve after surgical treatment of acute aortic dissection involving the ascending aorta. From 1972 to 1991, 93 patients underwent operation for type I or II aortic dissection. There were 76 men and 17 women. Mean age was 54 +/- 13 years. Eighty patients (86%) had a conservative procedure regarding the aortic root and aortic cusps: 74 had prosthetic replacement of the ascending aorta and 6, complete replacement of the aortic arch. Thirteen patients (14%) had simultaneous replacement of the aortic valve and the ascending aorta. The overall hospital mortality rate was 29% (27/93). The overall actuarial survival rate was 60.2% +/- 5.2%, 49.7% +/- 6.1%, and 35.9% +/- 8.1% at 5, 10, and 15 years, respectively. The survival rates for patients who had an ascending aortic procedure only were 63% +/- 5.5%, 54% +/- 6.5%, and 39% +/- 8.5% at 5, 10, and 15 years, respectively, and for patients who required aortic valve replacement, 45% +/- 14% and 22% +/- 17.5% at 5 and 10 years, respectively. Fifty long-term survivors (94% follow-up) with preservation of the aortic valve and aortic root were studied. Among them, 9 (18%) died within a mean interval of 97 +/- 46 months after operation. Causes of death were ischemic cardiac failure (2), aortic rupture or extension of dissection (4), renal disease (1), stroke (1), and sudden death (1). Forty-one patients had long-term clinical and echocardiographic evaluation.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是确定升主动脉急性主动脉夹层手术治疗后自体主动脉瓣的长期状况。1972年至1991年,93例患者接受了I型或II型主动脉夹层手术。其中男性76例,女性17例。平均年龄为54±13岁。80例患者(86%)在主动脉根部和主动脉瓣叶方面接受了保守手术:74例行升主动脉人工瓣膜置换术,6例行主动脉弓完全置换术。13例患者(14%)同时置换了主动脉瓣和升主动脉。总体医院死亡率为29%(27/93)。5年、10年和15年的总体精算生存率分别为60.2%±5.2%、49.7%±6.1%和35.9%±8.1%。仅接受升主动脉手术的患者5年、10年和15年的生存率分别为63%±5.5%、54%±6.5%和39%±8.5%,而需要置换主动脉瓣的患者5年和10年的生存率分别为45%±14%和22%±17.5%。对50例保留主动脉瓣和主动脉根部的长期存活者(随访率94%)进行了研究。其中9例(18%)在术后平均97±46个月内死亡。死亡原因包括缺血性心力衰竭(2例)、主动脉破裂或夹层扩展(4例)、肾病(1例)、中风(1例)和猝死(1例)。41例患者进行了长期临床和超声心动图评估。(摘要截短于250字)