Bruno R L, Galski T, DeLuca J
Post-Polio Rehabilitation and Research Service, Kessler Institute for Rehabilitation, East Orange, NJ 07018.
Arch Phys Med Rehabil. 1993 Oct;74(10):1061-5. doi: 10.1016/0003-9993(93)90062-f.
To test the hypothesis that post-polio fatigue and its concomitant cognitive deficits are associated with an impairment of attention and not of higher-level cognitive processes, six carefully screened polio survivors were administered a battery of neuropsychological tests. Only subjects reporting severe fatigue, and not those with mild fatigue, demonstrated clinically significant deficits on all tests of attention, concentration, and information processing speed while showing no impairments of cognitive ability or verbal memory. These findings suggest that an impaired ability to maintain attention and rapidly process complex information appears to be a characteristic in polio survivors reporting severe fatigue, because these deficits were documented even when their subjective rating of fatigue was low. This finding supports the hypothesis that a polio-related impairment of selective attention underlies polio survivors' subjective experience of fatigue and cognitive problems.
为了验证小儿麻痹后遗症疲劳及其伴随的认知缺陷与注意力受损而非高级认知过程受损有关这一假设，对六名经过仔细筛选的小儿麻痹症幸存者进行了一系列神经心理学测试。只有报告严重疲劳的受试者，而非轻度疲劳的受试者，在所有注意力、专注力和信息处理速度测试中表现出临床上显著的缺陷，同时未表现出认知能力或言语记忆受损。这些发现表明，维持注意力和快速处理复杂信息的能力受损似乎是报告严重疲劳的小儿麻痹症幸存者的一个特征，因为即使他们的疲劳主观评分较低，这些缺陷也得到了证实。这一发现支持了这样的假设，即小儿麻痹症相关的选择性注意力受损是小儿麻痹症幸存者疲劳和认知问题主观体验的基础。
