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本文引用的文献

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Sustained detection of type 2 poliovirus in London sewage between February and July, 2022, by enhanced environmental surveillance.2022 年 2 月至 7 月期间,通过强化环境监测,在伦敦污水中持续检测到 2 型脊髓灰质炎病毒。
Lancet. 2022 Oct 29;400(10362):1531-1538. doi: 10.1016/S0140-6736(22)01804-9. Epub 2022 Oct 13.
2
Public Health Response to a Case of Paralytic Poliomyelitis in an Unvaccinated Person and Detection of Poliovirus in Wastewater - New York, June-August 2022.公共卫生应对一例未接种疫苗的麻痹性脊髓灰质炎病例和废水中脊髓灰质炎病毒检测 - 纽约,2022 年 6 月至 8 月。
MMWR Morb Mortal Wkly Rep. 2022 Aug 19;71(33):1065-1068. doi: 10.15585/mmwr.mm7133e2.
3
Falls in Post-Polio Patients: Prevalence and Risk Factors.脊髓灰质炎后遗症患者的跌倒:患病率及危险因素
Biology (Basel). 2021 Oct 28;10(11):1110. doi: 10.3390/biology10111110.
4
Postpolio syndrome and the late effects of poliomyelitis. Part 1. pathogenesis, biomechanical considerations, diagnosis, and investigations.肌萎缩侧索硬化症与脊髓灰质炎的晚期效应。第 1 部分。发病机制、生物力学考虑、诊断和研究。
Muscle Nerve. 2018 Dec;58(6):751-759. doi: 10.1002/mus.26168. Epub 2018 Aug 22.
5
Aerobic Exercise Training in Post-Polio Syndrome: Process Evaluation of a Randomized Controlled Trial.脊髓灰质炎后遗症的有氧运动训练:一项随机对照试验的过程评估
PLoS One. 2016 Jul 15;11(7):e0159280. doi: 10.1371/journal.pone.0159280. eCollection 2016.
6
Test-Retest Reliability of the Self-Reported Impairments in Persons With Late Effects of Polio (SIPP) Rating Scale.小儿麻痹后遗症患者自我报告损伤(SIPP)评定量表的重测信度
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7
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8
Intravenous immunoglobulin for postpolio syndrome: a systematic review and meta-analysis.用于小儿麻痹后遗症的静脉注射免疫球蛋白:一项系统评价与荟萃分析。
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9
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[小儿麻痹后遗症诊断与神经康复治疗推荐指南]

[Guide of recommendations for the diagnosis and neurorrehabilitative treatment of post-poliomielytic sequelar conditions].

作者信息

Povedano Pandés Mónica, Rojas García Ricard, Querol Gutiérrez Luis, Rodríguez de Rivera Francisco Javier, Colomer Font Carolina, Noé Sebastián Enrique, Navarro Pérez Mª Dolores, Juárez Belaunde Alan, Ferri Campos Joan, Guijarro Castro Teresa Cristina

机构信息

Grupo de Estudio de Enfermedades Neuromusculares de la Sociedad Española de Neurología. Barcelona. España.

Sociedad Española de Neurorrehabilitación (SENR). España.

出版信息

Rev Esp Salud Publica. 2025 Jun 18;99:e202506006.

PMID:40530649
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12175752/
Abstract

Postpolio syndrome (PPS), which affects 20% to 50% of patients decades after initial poliovirus infection, poses a significant clinical challenge due to its unknown etiology and lack of pathogenic treatment. The main current theories point to degenerative processes secondary to the initial infection as the basis of its pathogenesis. Our guide addresses this complex landscape, providing a structured, evidence-based approach to the management of these sequelae. We emphasize the importance of: A personalized comprehensive evaluation; The development of multidisciplinary programs specifically designed to maximize functionality; Preventing complications and improving the quality of life of patients. We propose that these interventions be carried out under the supervision of an interdisciplinary team of specialists, who will use validated tools and personalized strategies based on the individual clinical characteristics of each patient. This approach ensures optimal functional benefit, aligned with current principles of evidence-based clinical practice.

摘要

小儿麻痹后遗症(PPS)在初次感染脊髓灰质炎病毒数十年后会影响20%至50%的患者,由于其病因不明且缺乏针对性治疗,构成了重大的临床挑战。目前的主要理论认为,继发于初次感染的退行性病变过程是其发病机制的基础。我们的指南阐述了这一复杂情况,提供了一种结构化的、基于证据的方法来管理这些后遗症。我们强调以下几点的重要性:个性化的全面评估;制定专门设计的多学科计划以最大限度地提高功能;预防并发症并改善患者的生活质量。我们建议这些干预措施在跨学科专家团队的监督下进行,该团队将根据每位患者的个体临床特征使用经过验证的工具和个性化策略。这种方法确保了最佳的功能效益,符合当前循证临床实践的原则。