Anderson D C
Department of Neurology, Hennepin County Medical Center, Minneapolis 55415.
Arch Neurol. 1993 Oct;50(10):1098-103. doi: 10.1001/archneur.1993.00540100083023.
To examine community practices.
Physician practice policies were surveyed using case vignettes in which evaluation for carotid endarterectomy or use of anticoagulation therapy was at issue. Virtually the same group was surveyed in 1988 and again in 1991, after publication of carotid endarterectomy trials in symptomatic patients.
Greater Metropolitan Minneapolis-St. Paul, Minnesota.
Community and academic neurologists in practice of general adult neurology.
Percentage of respondents who would recommend the management option in question for each vignette.
Ninety-eight percent favored evaluation for carotid endarterectomy in appropriately symptomatic "good risk" patients in 1988 before proof of efficacy became available. Proof increased the percentage (from 67% to 92%) favoring evaluation in older, sicker, symptomatic patients but not the percentage of those favoring evaluation of bruit patients (1988: 33%; 1991: 24%). In 1991, a lower percentage recommended warfarin therapy after noncardioembolic transient ischemic attack; this was especially apparent in the vertebrobasilar case (1988: 59%; 1991: 37%). Both years, nine of 10 neurologists recommended heparin therapy for progressing stroke, while half to three-fourths used it after partial stroke or transient ischemic attack. Almost all would use anticoagulants for secondary prophylaxis after suspected cardioembolic stroke.
The results reflect a treatment-oriented empirical approach in this community and document quick clinical application of scientific evidence when it became available.
研究社区医疗实践。
采用病例 vignettes 对医生的医疗实践政策进行调查,其中颈动脉内膜切除术的评估或抗凝治疗的使用存在争议。在有症状患者的颈动脉内膜切除术试验发表后,于1988年和1991年对几乎相同的群体进行了调查。
明尼苏达州明尼阿波利斯 - 圣保罗大都会区。
从事普通成人神经病学的社区和学术神经科医生。
针对每个 vignette,推荐所讨论管理方案的受访者百分比。
在1988年,在疗效证据出现之前,98% 的人赞成对症状适当、“风险良好”的患者进行颈动脉内膜切除术评估。证据的出现提高了对年龄较大、病情较重、有症状患者进行评估的比例(从67% 提高到92%),但对有杂音患者进行评估的比例没有提高(1988年:33%;1991年:24%)。1991年,在非心源性短暂性脑缺血发作后推荐使用华法林治疗的比例较低;在椎基底动脉病例中尤为明显(1988年:59%;1991年:37%)。在这两年中,十分之九的神经科医生推荐对进展性中风使用肝素治疗,而在部分中风或短暂性脑缺血发作后,有一半到四分之三的人使用肝素治疗。几乎所有人在疑似心源性栓塞性中风后会使用抗凝剂进行二级预防。
结果反映了该社区以治疗为导向的经验性方法,并记录了科学证据出现后在临床中的快速应用情况。