[Studies on percutaneous absorption of ruyi jinhuang san patcher with radioisotope tracer].

Berberine is one of the active ingredients in Ruyi Jinhuang San Patcher. With 3H-berberine as the tracer, a radio-labelled method was used for determining percutaneous rate and drug concentration of berberine in plasma in vivo and in vitro. A study on the percutaneous rate of different technological plasters and various animal skins was also carried out.