Subauste C S, Remington J S
Department of Immunology and Infectious Diseases, Palo Alto Medical Foundation, California 94301.
Curr Opin Immunol. 1993 Aug;5(4):532-7. doi: 10.1016/0952-7915(93)90034-p.
Recent advances in our understanding of the immunological mechanisms involved during infection with Toxoplasma gondii include evidence for the role of different subsets of lymphocytes and cytokines in acute infection as well as in reactivation of chronic infection. The mechanisms of presentation of T. gondii antigen have been clarified recently, and animal models of toxoplasmosis that mimic disease observed in AIDS patients developed.
我们对弓形虫感染过程中涉及的免疫机制的最新认识进展包括,有证据表明不同亚群的淋巴细胞和细胞因子在急性感染以及慢性感染再激活中发挥作用。弓形虫抗原呈递机制最近已得到阐明,并且已开发出模拟艾滋病患者所观察到疾病的弓形虫病动物模型。