Mishra S K, Staib F, Krumhaar D, Steffen J, Voigt R, Abel T
Dtsch Med Wochenschr. 1976 Sep 17;101(38):1377-81. doi: 10.1055/s-0028-1104276.
The incidence and distribution of aspergillosis among patients of a lung clinic in West Berlin were recorded. The immunodiffusion test (IDT) was used on sera of 228 patients seen during one day to test for precipitins against A. fumigatus, A. flavus, and A. niger. Precipitating antibodies specific against A. fumigatus were found in five patients, in two of them A. fumigatus was isolated simultaneously from sputum. In order to obtain a clear view of the clinical occurrence of asperigillosis and its course one requires not only serological tests but also the isolation of Aspergillus in culture from sputum or bronchial secretion. IDT is useful for detecting aspergillosis and for screening persons harbouring Aspergillus in their respiratory tract.
记录了西柏林一家肺部诊所患者中曲霉病的发病率和分布情况。对某一天就诊的228名患者的血清进行免疫扩散试验(IDT),以检测针对烟曲霉、黄曲霉和黑曲霉的沉淀素。在5名患者中发现了针对烟曲霉的特异性沉淀抗体,其中2名患者同时从痰液中分离出烟曲霉。为了清楚了解曲霉病的临床发生情况及其病程,不仅需要血清学检测,还需要从痰液或支气管分泌物中培养分离出曲霉菌。免疫扩散试验对于检测曲霉病以及筛查呼吸道携带曲霉菌的人很有用。