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[伴有多种肝外临床表现的慢性自身免疫性II型肝炎]

[Chronic autoimmune type II hepatitis with various extrahepatic clinical manifestations].

作者信息

Colome Pavón J A, Arranz García F, Viñuela Alejandre M A, Espinos Pérez D

机构信息

Servicio de Medicina I., Hospital Universitario San Carlos, Ciudad Universitaria, Madrid.

出版信息

An Med Interna. 1993 Aug;10(8):390-2.

PMID:8218784
Abstract

We present the case of a patient with autoimmune chronic hepatitis and anti-LKM antibodies, who developed associated autoimmune diseases, cyclic nodose erythema, bilateral peripheric paralysis, idiopathic thrombocytopenic purpura and diabetes mellitus. We describe the first signs of the disease and how three different forms can be differentiated depending on the type of autoantibodies present in the patients' serum. Finally, we list several forms of presentation of the disease, the potential clinical associations with other autoimmune processes and the potential immunological basis for the development of the hepatic lesion.

摘要

我们报告了一例患有自身免疫性慢性肝炎及抗肝肾微粒体抗体的患者,该患者并发了自身免疫性疾病、环状结节性红斑、双侧周围性麻痹、特发性血小板减少性紫癜和糖尿病。我们描述了该疾病的首发症状,以及如何根据患者血清中存在的自身抗体类型来区分三种不同的形式。最后,我们列举了该疾病的几种表现形式、与其他自身免疫过程的潜在临床关联以及肝脏病变发生的潜在免疫学基础。

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