Grasser K D, Wohlfarth T, Bäumlein H, Feix G
Institut für Biologie III, Albert-Ludwigs-Universität Freiburg, Germany.
Plant Mol Biol. 1993 Nov;23(3):619-25. doi: 10.1007/BF00019309.
Chromosomal high-mobility-group (HMG) proteins occur ubiquitously in eukaryotes and their common structural and biochemical features indicate a critical role. In this context, we compared structural and functional aspects of HMG proteins from the monocotyledonous plant maize and the dicotyledonous plant Vicia faba. Besides biochemical similarities and immunological differences found between these proteins, the isolation and characterization of a cDNA encoding the V. faba homologue of the maize HMGa protein revealed great similarities between these two proteins, including the HMG-box DNA-binding motif and an acidic domain. Therefore, like the maize HMGa protein, the V. faba HMG protein belongs to the vertebrate HMG1 family, which consists of HMG proteins and transcription factors of various eukaryotes.
染色体高迁移率族（HMG）蛋白普遍存在于真核生物中，其共同的结构和生化特征表明它们具有关键作用。在此背景下，我们比较了单子叶植物玉米和双子叶植物蚕豆中HMG蛋白的结构和功能方面。除了发现这些蛋白之间的生化相似性和免疫差异外，编码玉米HMGa蛋白蚕豆同源物的cDNA的分离和表征揭示了这两种蛋白之间的巨大相似性，包括HMG盒DNA结合基序和一个酸性结构域。因此，与玉米HMGa蛋白一样，蚕豆HMG蛋白属于脊椎动物HMG1家族，该家族由各种真核生物的HMG蛋白和转录因子组成。
