Lehnert T
Brookfield Cottage Hospital, Nfld.
Can Fam Physician. 1993 Oct;39:2157-62.
In a review and critical appraisal of the literature on antibiotic therapy for acute otitis media in children between 1939 and 1991, poor evidence supported the routine use of antibiotic therapy. Good evidence supported initial symptomatic treatment and institution of antibiotic therapy only in cases of an irregular course (fever or pain for more than 48 to 72 hours) in children 2 years and older. This approach cannot be recommended for children 2 years and younger because this age group has been excluded from most studies.
在对1939年至1991年间儿童急性中耳炎抗生素治疗文献的综述和批判性评估中，证据不足支持常规使用抗生素治疗。有力证据支持初始对症治疗，仅在2岁及以上儿童出现病程不规律（发热或疼痛超过48至72小时）的情况下使用抗生素治疗。对于2岁及以下儿童不推荐这种方法，因为该年龄组被排除在大多数研究之外。
