Franceschini V, Ciani F
Department of Biology, Bologna University, Italy.
Cell Mol Biol (Noisy-le-grand). 1993 Sep;39(6):651-8.
The binding of 14 lectins were performed on paraffin-embedded sections of the olfactory bulb of Triturus to identify specific glycoconjugates on the cell surface of primary olfactory projections. The histochemical lectin staining patterns indicate that the membrane of olfactory neurons terminating in the main olfactory bulb contained prevalently oligosaccharides with alpha-acetyl-D-galactosamine as terminal residues. In the accessory olfactory bulb, instead, the primary olfactory projections possess a high density of alpha-D-galactose as sugar residues. The selective lectin binding on the surface of primary olfactory axons suggests that specific cell surface glycoproteins may have a role in the axonal growth due to the continual cycle of proliferation and death of olfactory receptors.
对蝾螈嗅球石蜡包埋切片进行了14种凝集素结合实验，以鉴定初级嗅觉投射细胞表面的特定糖缀合物。组织化学凝集素染色模式表明，终止于主嗅球的嗅觉神经元膜中普遍含有以α-乙酰-D-半乳糖胺为末端残基的寡糖。相反，在副嗅球中，初级嗅觉投射具有高密度的α-D-半乳糖作为糖残基。初级嗅觉轴突表面的选择性凝集素结合表明，由于嗅觉受体不断的增殖和死亡循环，特定的细胞表面糖蛋白可能在轴突生长中起作用。
