• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Individual variability in p-aminobenzoic acid N-acetylation by human N-acetyltransferase (NAT1) of peripheral blood.

作者信息

Weber W W, Vatsis K P

机构信息

Department of Pharmacology, Medical School, University of Michigan, Ann Arbor 48109-0626.

出版信息

Pharmacogenetics. 1993 Aug;3(4):209-12. doi: 10.1097/00008571-199308000-00006.

DOI:10.1097/00008571-199308000-00006
PMID:8220441
Abstract
摘要

相似文献

1
Individual variability in p-aminobenzoic acid N-acetylation by human N-acetyltransferase (NAT1) of peripheral blood.人外周血N-乙酰转移酶（NAT1）对对氨基苯甲酸N-乙酰化的个体差异。
Pharmacogenetics. 1993 Aug;3(4):209-12. doi: 10.1097/00008571-199308000-00006.
2
Arylamine N-acetyltransferase 1 in situ N-acetylation on CD3+ peripheral blood mononuclear cells correlate with NATb mRNA and NAT1 haplotype.CD3+ 外周血单个核细胞中芳香胺 N-乙酰基转移酶 1 的原位 N-乙酰化与 NATb mRNA 和 NAT1 单倍型相关。
Arch Toxicol. 2018 Feb;92(2):661-668. doi: 10.1007/s00204-017-2082-y. Epub 2017 Oct 17.
3
Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations.由C190T和G560A突变引起的人类1型芳胺N - 乙酰基转移酶基因的功能多态性。
Pharmacogenetics. 1998 Feb;8(1):67-72. doi: 10.1097/00008571-199802000-00009.
4
Assessment of arylamine N-acetyltransferase (NAT1) activity in mononuclear leukocytes of cystic fibrosis patients.囊性纤维化患者单核白细胞中芳胺N - 乙酰转移酶（NAT1）活性的评估。
Br J Clin Pharmacol. 1995 Jan;39(1):85-9. doi: 10.1111/j.1365-2125.1995.tb04415.x.
5
Arylamine N-acetyltransferase in human red blood cells.人类红细胞中的芳胺N-乙酰基转移酶。
Biochem Pharmacol. 1992 Sep 25;44(6):1099-104. doi: 10.1016/0006-2952(92)90373-q.
6
Arylamine N-acetyltransferase activity of the human placenta.人胎盘的芳胺N - 乙酰基转移酶活性
J Pharmacol Exp Ther. 1994 May;269(2):756-60.
7
Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1).人类芳胺N-乙酰基转移酶1（NAT1）的基因型与表型之间的相关性
Biochem Pharmacol. 1999 Dec 1;58(11):1759-64. doi: 10.1016/s0006-2952(99)00269-5.
8
Expression of monomorphic arylamine N-acetyltransferase (NAT1) in human leukocytes.单态芳胺N - 乙酰转移酶（NAT1）在人白细胞中的表达
J Pharmacol Exp Ther. 1991 Dec;259(3):1241-6.
9
Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity.乙酰化酶表型分析：慢乙酰化者尿液中咖啡因代谢物的比例与全身NAT1活性标志物相关。
Pharmacogenetics. 1994 Jun;4(3):166-70.
10
4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.4-氨基联苯对快速和慢速乙酰化大鼠原代乳腺上皮细胞培养物中芳香族和杂环胺致癌物的NAT2乙酰化基因型依赖性N-和O-乙酰化的下调作用。
Toxicol Sci. 2009 Jan;107(1):293-7. doi: 10.1093/toxsci/kfn216. Epub 2008 Oct 8.

引用本文的文献

1
Physiologically Based Pharmacokinetic Modeling for Trimethoprim and Sulfamethoxazole in Children.基于生理的儿童体内甲氧苄啶和磺胺甲噁唑药代动力学模型。
Clin Pharmacokinet. 2019 Jul;58(7):887-898. doi: 10.1007/s40262-018-00733-1.
2
Retrospective analysis of estrogen receptor 1 and N‑acetyltransferase gene expression in normal breast tissue, primary breast tumors, and established breast cancer cell lines.雌激素受体 1 和 N-乙酰基转移酶基因在正常乳腺组织、原发性乳腺癌肿瘤和建立的乳腺癌细胞系中的表达的回顾性分析。
Int J Oncol. 2018 Aug;53(2):694-702. doi: 10.3892/ijo.2018.4436. Epub 2018 Jun 11.
3
N-Acetyltransferase 1 (NAT1) Genotype: A Risk Factor for Urinary Bladder Cancer in a Lebanese Population.
N-乙酰基转移酶 1（NAT1）基因型：黎巴嫩人群膀胱癌的风险因素。
J Oncol. 2012;2012:512976. doi: 10.1155/2012/512976. Epub 2012 Aug 22.
4
Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase.铜绿假单胞菌芳胺N-乙酰基转移酶的表达、纯化、特性及结构
Biochem J. 2005 Jan 15;385(Pt 2):605-12. doi: 10.1042/BJ20041330.
5
NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant.NAT基因多态性与阿尔茨海默病易感性：一种新型NAT1等位基因变异的鉴定
BMC Med Genet. 2004 Mar 17;5:6. doi: 10.1186/1471-2350-5-6.
6
Polymorphism of N-acetyltransferase 1 and correlation between genotype and phenotype in a Thai population.
Eur J Clin Pharmacol. 2003 Aug;59(4):277-81. doi: 10.1007/s00228-003-0630-2. Epub 2003 Jul 19.
7
Genetic polymorphisms of N-acetyltransferase 1 and 2 and risk of cigarette smoking-related bladder cancer.N-乙酰基转移酶1和2的基因多态性与吸烟相关膀胱癌的风险
Br J Cancer. 1999 Oct;81(3):537-41. doi: 10.1038/sj.bjc.6690727.
8
Cloning and characterization of arylamine N-acetyltransferase genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: increased expression results in isoniazid resistance.耻垢分枝杆菌和结核分枝杆菌芳胺N-乙酰基转移酶基因的克隆与特性分析：表达增加导致异烟肼耐药。
J Bacteriol. 1999 Feb;181(4):1343-7. doi: 10.1128/JB.181.4.1343-1347.1999.
9
N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients.N-乙酰转移酶1：在结直肠癌患者中鉴定出的编码序列中的两种多态性。
Br J Cancer. 1998 Mar;77(6):913-6. doi: 10.1038/bjc.1998.151.
10
Acetylation as an indicator of risk.乙酰化作为风险指标。
Environ Health Perspect. 1997 Jun;105 Suppl 4(Suppl 4):763-6. doi: 10.1289/ehp.97105s4763.