Tomioka S, Kobayashi Y
Jpn J Antibiot. 1976 Jun;29(6):597-600.
In vitro synergism of sulbenicillin and dibekacin was investigated with 19 strains of E. coli, 20 strains of Enterobacter and 20 strains of Pseudomonas aeruginosa on agar plates. As the results, sulbenicillin and dibekacin were found to be synergistically bacteriostatic against all these organisms, though the synergistic effects were somewhat less potent against E. coli. The concentrations of dibekacin required for assuming a clear synergism were 0.78 approximately 1.56 mug/ml.
在琼脂平板上,用19株大肠杆菌、20株肠杆菌和20株铜绿假单胞菌研究了磺苄西林和地贝卡星的体外协同作用。结果发现,磺苄西林和地贝卡星对所有这些微生物均有协同抑菌作用,尽管对大肠杆菌的协同作用稍弱。呈现明显协同作用所需的地贝卡星浓度约为0.78至1.56微克/毫升。