多拷贝SUP35基因诱导酿酒酵母中类似ψ因子的从头出现。
Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae.
作者信息
Chernoff Y O, Derkach I L, Inge-Vechtomov S G
机构信息
Department of Genetics, Saint-Petersburg University, Russia.
出版信息
Curr Genet. 1993 Sep;24(3):268-70. doi: 10.1007/BF00351802.
PMID:8221937
Abstract
Previously, we have shown that plasmid-mediated multiplication of Saccharomyces cerevisiae wild-type SUP35 gene leads to omnipotent suppression and is incompatible with psi-factor, which is an endogenous extrachromosomal suppressor. Here, we describe a frequent de-novo appearance of psi-like factors in mitotic progeny of yeast transformants containing multicopy SUP35 gene.
摘要
此前，我们已经表明，质粒介导的酿酒酵母野生型SUP35基因的倍增会导致全能抑制，并且与ψ因子不相容，ψ因子是一种内源性的染色体外抑制因子。在此，我们描述了在含有多拷贝SUP35基因的酵母转化体的有丝分裂后代中，ψ样因子频繁地从头出现。
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