Xie X B, Liu Y N
Department of pulmonary medicine, General hospital of PLA air force, Beijing.
Zhonghua Jie He He Hu Xi Za Zhi. 1993 Feb;16(2):98-100, 124-5.
Arterial blood, arterialized capillary blood, transcutaneous, end tidal carbon dioxide pressure (PaCO2, PcCO2, PtcCO2, PetCO2) and physiological respiratory deadspace to tidal volume ratio (VD/VT) were observed in 12 patients with chronic obstructive pulmonary disease (group A), 17 postoperative patients of cardiac surgery (group B), and 16 healthy subjects (group C) under three mechanical ventilatory patterns. PcCO2, PtcCO2 and PetCO2 were found to correlate well with PaCO2 (r = 0.99, 0.97 and 0.88 respectively); P(a-et) CO2 correlated with age (year) in group B and C (r = 0.77 and 0.76), and all P(a-et) CO2 measurements of each of three groups highly correlated with VD/VT (r = 0.96 0.91 and 0.87 for group A,B,C respectively). The results suggested that the trend of PaCO2 variation can be deduced from PcCO2, PtcCO2 and PetCO2 with fair accuracy under various ventilatory patterns in subjects with stable circulatory function, and P(a-et) CO2 is a simple quantitative index for evaluating physiological deadspace.
在三种机械通气模式下，对12例慢性阻塞性肺疾病患者（A组）、17例心脏手术后患者（B组）和16名健康受试者（C组）观察了动脉血、动脉化毛细血管血、经皮、呼气末二氧化碳分压（PaCO2、PcCO2、PtcCO2、PetCO2）以及生理死腔与潮气量比值（VD/VT）。发现PcCO2、PtcCO2和PetCO2与PaCO2具有良好的相关性（r分别为0.99、0.97和0.88）；B组和C组中P（a-et）CO2与年龄（岁）相关（r分别为0.77和0.76），并且三组中各P（a-et）CO2测量值与VD/VT均高度相关（A组、B组、C组的r分别为0.96、0.91和0.87）。结果表明，在循环功能稳定的受试者中，在各种通气模式下，可从PcCO2、PtcCO2和PetCO2以相当的准确性推断出PaCO2变化趋势，且P（a-et）CO2是评估生理死腔的一个简单定量指标。
