de Gandarias J M, Irazusta J, Echevarria E, Casis L
Department of Physiology, Medical School, University of the Basque Country, Bilbao, Spain.
Exp Clin Endocrinol. 1993;101(3):156-60. doi: 10.1055/s-0029-1211223.
The present report describes the activity of aspartate aminopeptidase, in 9 brain areas and in the pituitary gland, during the estrous cycle and several stages of pregnancy of the rat. The quantitation of the enzyme activity was performed by measuring the rate of hydrolysis of the chromogenic substrate Asp-beta-naphthylamide. Aspartate aminopeptidase activity, in the pituitary gland and in several limbic areas, was found to be greater in cyclic than in pregnant rats. However the enzyme activity did not change significantly during either the estrous cycle and pregnancy.
本报告描述了大鼠发情周期和妊娠几个阶段中，9个脑区和垂体中天冬氨酸氨基肽酶的活性。通过测量发色底物天冬氨酸-β-萘酰胺的水解速率来进行酶活性的定量。结果发现，垂体和几个边缘脑区中的天冬氨酸氨基肽酶活性，处于发情周期的大鼠比妊娠大鼠更高。然而，在发情周期和妊娠期，该酶活性均未发生显著变化。
