Ultrastructural changes in rat mammotropes following incubation with dopamine.
作者信息
Joneja M, Reifel C W, Murphy M L, Shin S H
机构信息
Department of Anatomy, Queen's University, Kingston, Ontario, Canada.
出版信息
Experientia. 1993 Oct 15;49(10):836-9. doi: 10.1007/BF01952593.
PMID:8224096
Abstract
Cultured mammotropes incubated with dopamine for one hour exhibited changes in ultrastructure indicative of actively depressed biosynthetic and secretory activity. Peripheral relocation of rough endoplasmic reticulum appeared to create a barrier to secretory granule release by exocytosis. A decrease in the numbers of secretory granules indicated a decrease in prolactin production and enhanced lysosomal activity.
摘要
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