在使用促性腺激素诱导排卵的随访中，排卵前卵巢扫描无法预测多胎妊娠的发生。
The inability of preovulatory ovarian scan to predict multifetal pregnancy occurrence in a follow-up of induction of ovulation with menotropins.
作者信息
Ben-Nun I, Cohen I, Shulman A, Fejgin M, Goldberger S, Beyth Y
机构信息
Department of Obstetrics and Gynecology, Sapir Medical Center, Kfar Saba, Israel.
出版信息
Fertil Steril. 1993 Nov;60(5):781-5. doi: 10.1016/s0015-0282(16)56276-1.
OBJECTIVE
To establish the predictive role of preovulatory ovarian ultrasonography in the occurrence of multiple pregnancy after hMG and hCG treatment for anovulatory infertility.
DESIGN
Prospective.
SETTING
Outpatient Infertility Clinic.
PATIENTS
Ninety-five anovulatory women who conceived after gonadotropin therapy.
INTERVENTION
Induction of ovulation by hMG and hCG monitored by plasma E2 measurements and ovarian ultrasonography.
MAIN OUTCOME MEASURES
All follicles visualized on the day of hCG administration were recorded and divided into the following four groups: group I, 10 to 12 mm; group II, 13 to 15 mm; group III, 16 to 18 mm; and group IV, 19 mm and larger. The sonographic findings were statistically evaluated to 80 singletons and 45 multiple pregnancies.
RESULTS
No statistical correlation was found to exist between the number of follicles from the different groups and the number of fetuses.
CONCLUSIONS
The number and sizes of follicles visualized on the day of hCG administration have no predictive value regarding the occurrence of a multiple pregnancy.
目的
确立排卵前卵巢超声检查对无排卵性不孕症患者接受人绝经期促性腺激素（hMG）和人绒毛膜促性腺激素（hCG）治疗后发生多胎妊娠的预测作用。
设计
前瞻性研究。
地点
门诊不孕症诊所。
患者
95名接受促性腺激素治疗后受孕的无排卵女性。
干预
通过血浆雌二醇（E2）测定和卵巢超声检查监测hMG和hCG诱导排卵。
主要观察指标
记录hCG给药当天可见的所有卵泡，并分为以下四组：I组，10至12毫米；II组，13至15毫米；III组，16至18毫米；IV组，19毫米及更大。对80例单胎妊娠和45例多胎妊娠的超声检查结果进行统计学评估。
结果
未发现不同组卵泡数量与胎儿数量之间存在统计学相关性。
结论
hCG给药当天可见的卵泡数量和大小对多胎妊娠的发生没有预测价值。
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