对果蝇中包含节段极性基因costa以及细胞极性基因prickle和spiny-legs的43A-E区域进行遗传和细胞遗传学分析。
Genetic and cytogenetic analysis of the 43A-E region containing the segment polarity gene costa and the cellular polarity genes prickle and spiny-legs in Drosophila melanogaster.
作者信息
Heitzler P, Coulson D, Saenz-Robles M T, Ashburner M, Roote J, Simpson P, Gubb D
机构信息
Laboratoire de Génétique Moléculaire des Eucaryotes du CNRS, Unité 184 de Biologie Moléculaire et de Génie Génétique de l'INSERM, Faculté de Médicine, Strasbourg, France.
出版信息
Genetics. 1993 Sep;135(1):105-15. doi: 10.1093/genetics/135.1.105.
Abstract
A cytogenetic analysis of the 43A-E region of chromosome 2 in Drosophila melanogaster is presented. Within this interval 27 complementation groups have been identified by extensive F2 screens and ordered by deletion mapping. The region includes the cellular polarity genes prickle and spiny-legs, the segmentation genes costa and torso, the morphogenetic locus sine oculis and is bounded on its distal side by the eye-color gene cinnabar. In addition 19 novel lethal complementation groups and two semi-lethal complementation groups with morphogenetic escaper phenotypes are described.
摘要
本文介绍了对黑腹果蝇2号染色体43A-E区域的细胞遗传学分析。在这个区间内，通过广泛的F2筛选鉴定出了27个互补群，并通过缺失作图进行了排序。该区域包括细胞极性基因prickle和spiny-legs、体节基因costa和torso、形态发生位点sine oculis，其远端由眼色基因朱砂（cinnabar）界定。此外，还描述了19个新的致死互补群和两个具有形态发生逃逸表型的半致死互补群。
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