MacLeod D, Kane B, Kidney D, Murphy J, O'Briain D S, Jackson F, Mulvihill B, Mulcahy F, Clancy L, Prichard J S
Department of Respiratory Medicine, St. James' Hospital, Dublin.
Ir Med J. 1993 Sep-Oct;86(5):167-9.
We investigated lung pathology in 61 HIV-positive patients who underwent 79 bronchoscopies. There were 27 cases of pneumocystis carinii pneumonia (PCP), 22 cases of pyogenic pulmonary infection and six cases of mycobacterial infection. Eleven cases of non-specific interstitial pneumonitis were found and 10 intravenous drug abusers had birefringent pulmonary talc granulomata in biopsy specimens. Women and intravenous drug abusers had higher rates of pyogenic pulmonary infection than men and other risk groups respectively. When compared with a previous survey from the same hospital using the same methodology the present study showed a change in the risk groups with 50% more intravenous drug abusers, 42% more haemophiliacs and 45% fewer patients with sexually transmitted infection. However, apparent changes in the spectrum of diseases encountered were not significant.
我们对61例接受了79次支气管镜检查的HIV阳性患者的肺部病理情况进行了调查。其中有27例卡氏肺孢子虫肺炎（PCP）、22例化脓性肺部感染和6例分枝杆菌感染。发现11例非特异性间质性肺炎，10例静脉吸毒者的活检标本中有双折射性肺滑石肉芽肿。女性和静脉吸毒者化脓性肺部感染的发生率分别高于男性和其他风险组。与同一家医院之前采用相同方法进行的调查相比，本研究显示风险组发生了变化，静脉吸毒者增加了50%，血友病患者增加了42%，性传播感染患者减少了45%。然而，所遇到疾病谱的明显变化并不显著。
