Griego L C
Medical/Cardiac Intensive Care Unit, University Hospital, Albuquerque, NM 87106.
Heart Lung. 1993 Sep-Oct;22(5):392-400.
To examine physiologic and psychologic factors contributing to depression in patients one year after myocardial infarction.
Convenience, correlational design.
A university-affiliated cardiology clinic, a health maintenance organization, and a private cardiology group in a southwestern city.
Fifteen men and six women 10 to 14 months after myocardial infarction.
Oxygen saturation, somatic symptoms, and functional status in three areas (social, physical, and emotional) were correlated to depression scores by use of the Zung Self-rating Depression Scale (SDS) and the Symptom Questionnaire (SQ).
Spearman rho correlations showed that depression measured with the Zung SDS and SQ depression subscale were inversely related to somatic symptoms, social function, physical function, emotional function, and total function. There was a significant inverse relationship between depression 9as measured by the Zung SDS) and both oxygen saturation and physical function. Although there was an inverse relationship between depression (as measured by the SQ subscale) and both oxygen saturation and physical function, it was not statistically significant. A Mann-Whitney U test for differences showed that mean SDS scores for Hispanic subjects (n = 5) and white subjects (n = 16) differed significantly. Stepwise multiple regression showed that overall functional status accounted for 56% of the variance for depression in the SDS and for 59% in the SQ depression subscale. Oxygen saturation accounted for less than 1% of the variance in both depression scales.
The results of this study indicate that depression is negatively correlated with overall functional status in a select group of patients one year after myocardial infarction. A moderate negative correlation was also found between depression and hypoxia. Hispanic subjects had significant differences in their mean Zung SDS scores as compared with white subjects.
研究心肌梗死后一年患者发生抑郁的生理和心理因素。
便利抽样、相关性设计。
西南部城市的一家大学附属医院心内科门诊、一个健康维护组织以及一个私人心脏病学小组。
心肌梗死后10至14个月的15名男性和6名女性。
采用zung自评抑郁量表（SDS）和症状问卷（SQ），将氧饱和度、躯体症状以及三个方面（社会、身体和情感）的功能状态与抑郁评分进行相关性分析。
Spearman等级相关分析显示，用zung SDS和SQ抑郁分量表测得的抑郁与躯体症状、社会功能、身体功能、情感功能及总功能呈负相关。（用zung SDS测得的）抑郁与氧饱和度和身体功能之间存在显著负相关。尽管（用SQ分量表测得的）抑郁与氧饱和度和身体功能之间呈负相关，但无统计学意义。Mann-Whitney U检验差异显示，西班牙裔受试者（n = 5）和白人受试者（n = 16）的平均SDS得分存在显著差异。逐步多元回归分析显示，总体功能状态在SDS抑郁量表中占抑郁变异的56%，在SQ抑郁分量表中占59%。氧饱和度在两个抑郁量表中所占变异均小于1%。
本研究结果表明，在一组心肌梗死后一年的特定患者中，抑郁与总体功能状态呈负相关。抑郁与低氧血症之间也存在中度负相关。与白人受试者相比，西班牙裔受试者的平均zung SDS得分存在显著差异。
