Fukuda M, Kitajima J, Fushida H, Hamada T
Department of Dermatology, Osaka City University Medical School, Japan.
J Dermatol. 1993 Sep;20(9):561-5. doi: 10.1111/j.1346-8138.1993.tb01339.x.
We report a 22-year-old man with acquired dermal melanocytosis on the hand which developed without any history of previous inflammation. He had no history of contact with or oral administration of any drugs or metals which might have caused pigmentation. Histopathologically, spindle-shaped dermal melanocytes were observed running parallel to the collagen bundles and scattered in all portions of the dermis. The dopa reaction of these cells was positive. Ultrastructurally, dermal melanocytes containing numerous melanosomes (stages II to IV) which were surrounded by the extracellular sheath were observed. Differential diagnosis of other dermal melanocytosis was discussed.
我们报告一名22岁男性，手部患有获得性皮肤黑素细胞增多症，其发生时无前驱炎症病史。他没有接触或口服任何可能导致色素沉着的药物或金属的病史。组织病理学检查显示，梭形真皮黑素细胞与胶原束平行排列，并散在于真皮各层。这些细胞的多巴反应呈阳性。超微结构观察发现，真皮黑素细胞含有大量被细胞外鞘包围的黑素小体（II至IV期）。文中讨论了其他皮肤黑素细胞增多症的鉴别诊断。
