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[大量胎儿-母体出血与胎儿-母体恒河猴血型不相容的预防。我们现行预防体系的失败]

[Massive fetomaternal hemorrhage and prevention of fetomaternal Rhesus incompatibility. The failure of our present system of prevention].

作者信息

Quartier P, Floch C, Meier F, Fruchart M F, Brossard Y, Lejeune C

机构信息

Service de Néonatologie, Hôpital Louis-Mourier, Colombes.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1993;22(5):517-9.

PMID:8228016
Abstract

We had a case where risk of rhesus D feto-maternal immunisation occurred following failure to diagnose feto-maternal haemorrhage (HFM); and it was shown up by rhesus negative mother with a rhesus positive fetus being diagnosed as having has a massive HFM only three days after delivery. Giving the mother the standard dose of Anti-D immunoglobulin without a previous test to find out how serious the HFM was showed that we do not test for this normally. So it seems to us necessary when considering prophylaxis of rhesus D immunisation to go back to first principles and carry out Kleihauer's test particularly when neonatal anaemia is found in the child.

摘要

我们遇到过这样一个病例,由于未能诊断出胎儿-母体出血(HFM),发生了恒河猴D型母婴免疫的风险;一名Rh阴性母亲和Rh阳性胎儿,在分娩后三天才被诊断出患有大量HFM。在没有事先检测以确定HFM严重程度的情况下,给母亲注射标准剂量的抗D免疫球蛋白,这表明我们通常不会对此进行检测。因此,在我们看来,在考虑预防恒河猴D免疫时,有必要回归基本原则并进行克莱豪尔试验,特别是当在儿童中发现新生儿贫血时。

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