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首个癌胚抗原（CEA）英国标准。

First British standard for carcinoembryonic antigen (CEA).

作者信息

Laurence D J, Turberville C, Anderson S G, Neville A M

出版信息

Br J Cancer. 1975 Sep;32(3):295-9. doi: 10.1038/bjc.1975.227.

DOI:10.1038/bjc.1975.227
PMID:822862
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2024740/
Abstract

In 1974, the National Institute for Biological Standards and Control (NIBSC) established the first British Standard for carcinoembryonic antigen (CEA) for use in comparative quantitative assays. The Standard, which was prepared for material processed by the Chester Beatty Research Institute, is in the form of a freeze-dried powder, sealed in all glass ampoules code labelled 73/601 and containing pure dry nitrogen. For practical purposes, each ampoule contains 100 units of CEA activity.

摘要

1974年，英国国家生物标准与控制研究所（NIBSC）制定了首个用于比较定量分析的癌胚抗原（CEA）英国标准。该标准是为切斯特·比蒂研究所处理的材料制备的，呈冻干粉末形式，密封在所有玻璃安瓿中，编码为73/601，并含有纯干燥氮气。实际使用中，每个安瓿含有100单位的CEA活性。

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DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.通过免疫耐受和吸收技术证明人类结肠癌中的肿瘤特异性抗原
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Role of plasma carcinoembryonic antigen in diagnosis of gastrointestinal, mammary, and bronchial carcinoma.血浆癌胚抗原在胃肠道、乳腺癌和支气管癌诊断中的作用。
Br Med J. 1972 Sep 9;3(5827):605-9. doi: 10.1136/bmj.3.5827.605.
6
Structural studies of the major glycoprotein in preparations with carcinoembryonic antigen activity.具有癌胚抗原活性的制剂中主要糖蛋白的结构研究。
J Exp Med. 1972 Jul 1;136(1):200-4. doi: 10.1084/jem.136.1.200.
7
The determination of carbohydrate in biological materials by gas-liquid chromatography.用气相色谱法测定生物材料中的碳水化合物。
Methods Biochem Anal. 1971;19:229-344. doi: 10.1002/9780470110386.ch3.
8
Studies on carcinoembryonic antigen (CEA) and a related glycoprotein, CCEA-2. Preparation and chemical characterisation.癌胚抗原（CEA）及相关糖蛋白CCEA - 2的研究。制备与化学特性分析。
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9
Studies on the structure of the carcinoembryonic antigen. I. some deductions on the basis of chemical degradations.癌胚抗原结构的研究。I. 基于化学降解的一些推断。
Immunochemistry. 1974 Dec;11(12):811-8. doi: 10.1016/0019-2791(74)90302-4.
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Physicochemical studies of the carcinoembryonic antigens of the human digestive system.人类消化系统癌胚抗原的物理化学研究。
J Exp Med. 1968 Sep 1;128(3):387-98. doi: 10.1084/jem.128.3.387.