Chalfie M
Department of Biological Sciences, Columbia University, New York, New York 10027.
J Neurobiol. 1993 Oct;24(10):1433-41. doi: 10.1002/neu.480241013.
Mutations causing a touch-insensitive phenotype in the nematode Caenorhabditis elegans have been the basis of studies on the specification of neuronal cell fate, inherited neurodegeneration, and the molecular nature of mechanosensory transduction.
在线虫秀丽隐杆线虫中导致触觉不敏感表型的突变,一直是神经元细胞命运的特化、遗传性神经退行性变以及机械感觉转导的分子本质等研究的基础。