Harris N V, Thiede H, McGough J P, Gordon D
Seattle-King County Department of Public Health, Washington 98104.
J Acquir Immune Defic Syndr (1988). 1993 Nov;6(11):1275-82.
Among injection drug users (IDUs) entering drug treatment in King County, Washington between 1988 and 1991, we investigated HIV seroprevalence in relationship to demographic, sexual, and drug-use characteristics. Eighty-two of 3,039 (2.7%) IDUs tested HIV positive. Gay or bisexual men had the highest HIV prevalence (37.1%), followed by lesbian or bisexual women (8.3%), heterosexual men (2.3%), and heterosexual women (1.5%). American Indians were more likely to be infected with HIV than were whites. Those with no permanent address were more likely to be infected than those with an address. Unexpectedly, the prevalence of HIV infection among amphetamine injectors (13.1% of 168) was higher than among those who did not report using amphetamines. After adjustment for sexual orientation, HIV prevalence was four times higher among primary amphetamine injectors and three times higher among secondary amphetamine injectors than among injectors of other drugs. The basis for the strong association observed between HIV infection and a history of injection of amphetamines is not known and should be clarified through further research that obtains more detailed information on IDUs.
在1988年至1991年间进入华盛顿州金县接受戒毒治疗的注射吸毒者中，我们调查了艾滋病毒血清流行率与人口统计学、性行为及吸毒特征之间的关系。3039名注射吸毒者中有82人（2.7%）艾滋病毒检测呈阳性。男同性恋或双性恋男性的艾滋病毒感染率最高（37.1%），其次是女同性恋或双性恋女性（8.3%）、异性恋男性（2.3%）和异性恋女性（1.5%）。美洲印第安人比白人更易感染艾滋病毒。无固定住址者比有固定住址者更易感染。出乎意料的是，苯丙胺注射者中的艾滋病毒感染率（168人中的13.1%）高于未报告使用苯丙胺者。在对性取向进行调整后，主要注射苯丙胺者的艾滋病毒感染率比其他毒品注射者高四倍，次要注射苯丙胺者高两倍。艾滋病毒感染与苯丙胺注射史之间存在密切关联的原因尚不清楚，应通过进一步研究获取关于注射吸毒者更详细信息来加以阐明。
